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Scientists at the CSIR-Centre for Cellular and Molecular Biology “identified, for the first time, that the gene TEX13B is essential for sperm” in a recent multi-institutional study read more
 "Faulty gene from mother can be behind son's infertility, says new study")
Male factors, such as low sperm count, aberrant sperm motility, and abnormal sperm size and shape, are responsible for half of all cases of infertility caused by abnormal semen parameters
For the first time, researchers from the CSIR-Centre for Cellular and Molecular Biology in Hyderabad as well as other universities have determined that the X chromosome gene (TEX13B) is necessary for the formation of sperm cells and male fertility.
On Thursday, May 16, the CSIR-Centre for Cellular and Molecular Biology (CCMB) reported that, globally, almost one in seven couples are infertile.
Male factors, such as low sperm count, aberrant sperm motility, and abnormal sperm size and shape, are responsible for half of all cases of infertility caused by abnormal semen parameters.
The genetic component is one of the key elements behind these causes.
Scientists at the CSIR-Centre for Cellular and Molecular Biology “identified, for the first time, that the gene TEX13B is essential for sperm” in a recent multi-institutional study.
“Using next generation sequencing, we compared all the gene coding regions (exons) between infertile and fertile males. We found two causative mutations in the TEX13B gene, of which one was exclusively found in infertile men and other one is found much more frequently in infertile men compared to fertile control men,” said Umesh Kumar, the first author who was a PhD student of CCMB.
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